Phosphine Ligands
Phosphine ligands serve as crucial components in transition metal catalysis for pharmaceutical synthesis and bioconjugation. Our high-purity ligands feature:
- Chiral phosphines (BINAP, DuPhos) for asymmetric hydrogenation
- Water-soluble variants (TPPTS, sulfonated ligands) for biocompatible cross-coupling
- Bidentate systems (dppe, Xantphos) for stabilizing reactive intermediates
• Precise control of metal coordination geometry
• Enhanced catalytic efficiency in C-C/N bond formations
• Tailored steric/electronic properties (Tolman parameters)
These ligands enable efficient synthesis of chiral drugs, antibody-drug conjugates (ADCs), and radiolabeled compounds under mild conditions.
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