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L-3-n-Butylphthalide - CAS 3413-15-8
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OMYZ001
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L-3-n-Butylphthalide

suitable for , ≥99%
Synonym(s): (S)-(-)-3-n-Butylphthalide
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Product Information
General Properties
Other Properties
Description
Safety Information
Product Information
CAS Number 3413-15-8
Linear Formula

C12H14O2

Molecular weight 190.23836
Beilstein
EC Number

MDL Number

PubChem CID
PubChem SID
General Properties
Purity 99%
Solubility DMSO: 10 mg/ml,Ethanol: 10 mg/ml
Storage Conditions -20°C
SMILES string CCCC[C@H]1C2=CC=CC=C2C(O1)=O
Other Properties
DESCRIPTION
L-3-n-Butylphthalide is a phthalide that has been found in A. graveolens and has antiplatelet and neuroprotective activities.1 It inhibits ADP-, collagen-, and arachidonic acid-induced platelet aggregation ex vivo when administered at doses ranging from 3 to 100 mg/kg and inhibits thrombus formation in a collagen and epinephrine-induced rat model of experimental thrombosis. L-3-n-Butylphthalide (10 and 30 mg/kg per day) reduces amyloid-β-induced decreases in glutathione peroxidase (GPX) activity and decreases malondialdehyde (MDA) levels in the cortex and hippocampus and improves spatial learning and memory in the Morris water maze in a rat model of Alzheimer’s disease induced by intracerebroventricular infusion of amyloid-β (1-40) 
SAFETY INFORMATION
  • Symbol GHS

  • Hazard Code

  • Risk Statements

  • Safety Statements

  • RIDADR

  • WGK Germany

  • RTECS

  • F

  • Hazard Class

  • Packing Group

  • HS Code

  • Toxicity

  • Autoignition Temperature

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