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COO/COA

OCY706
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Cyanine7 alkyne
suitable for HPLC, ≥95%
Synonym(s): Cy7-alkyne
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Pack Size SKU Availability Price Quantity
1mg OCY706-1mg In stock $112.00
- +
5mg OCY706-5mg In stock $234.00
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10mg OCY706-10mg In stock $349.00
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25mg OCY706-25mg In stock $459.00
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50mg OCY706-50mg In stock $805.00
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Product Information
General Properties
Other Properties
Description
Safety Information
Product Information
CAS Number
Linear Formula

C37H44ClN3O

Molecular weight 582.23
Beilstein
EC Number

MDL Number

PubChem CID
PubChem SID
General Properties
Purity 95%
Appearance Dark blue powder
Solubility Freely soluble in methanol, chloroform, DMSO, and DMF; poorly soluble in water.
Purity Testing Method HPLC
Structural Identification Method NMR/MS
Storage Conditions −20 °C, keep in dark place.
Other Properties
DESCRIPTION

Cyanine7 Alkyne is a click chemistry reagent (ex/em 750/773 nm) for copper-catalyzed (CuAAC) or strain-promoted (SPAAC) cycloadditions with azides. This non-sulfonated near-infrared dye enables efficient bioorthogonal conjugation to azide-functionalized biomolecules while maintaining deep-tissue imaging capabilities. Exhibits excellent solubility in organic solvents (e.g., DMSO) and limited aqueous compatibility.
For aqueous applications, use sulfo-Cyanine7 Azide. Store desiccated at -20°C under inert atmosphere.

SAFETY INFORMATION
  • Symbol GHS

  • Hazard Code

  • Risk Statements

  • Safety Statements

  • RIDADR

  • WGK Germany

  • RTECS

  • F

  • Hazard Class

  • Packing Group

  • HS Code

  • Toxicity

  • Autoignition Temperature

RELATED PRODUCTS
REFERENCES
1. Zhang, L.; Thurber, G.M. Quantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging. Molecular Imaging and Biology, 2016, 18(1), 79–89. doi: 10.1007/s11307-015-0880-2
2. Smith, A.A.A.; Zuwala, K.; Pilgram, O.; Johansen, K.S.; Tolstrup, M.; Dagn?s-Hansen, F.; Zelikin, A.N. Albumin-Polymer-Drug Conjugates: Long Circulating, High Payload Drug Delivery Vehicles. ACS Macro Letters, 2016, 5, 1089–1094. doi: 10.1021/acsmacrolett.6b00544
3. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
4. Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
5. Hwang, D.; Nilchan, N.; Nanna, A.R.; Li, X.; Cameron, M.D.; Roush, W.R.; Park, H.; Rader, C. Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. Cell Chemical Biology, 2019, 26(9), 1229–1239. doi: 10.1016/j.chembiol.2019.05.010
6. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
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