Cyanine7 NHS ester

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SDS

COO/COA

OCY702

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Cyanine7 NHS ester

suitable for HPLC, ≥95%

Synonym(s): Cy7-NHS

Select a Size

Pack Size	SKU	Availability	Price	Quantity
1mg	OCY702-1mg	In stock	$112.00	- +
5mg	OCY702-5mg	In stock	$234.00	- +
10mg	OCY702-10mg	In stock	$349.00	- +
25mg	OCY702-25mg	In stock	$459.00	- +
50mg	OCY702-50mg	In stock	$805.00	- +

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Product Information

General Properties

Other Properties

Description

Safety Information

Product Information

CAS Number
Linear Formula	C₃₈H₄₄ClN₃O₄
Molecular weight	642.23
Beilstein
EC Number
MDL Number
PubChem CID
PubChem SID

General Properties

Purity	95%
Appearance	Dark blue powder
Solubility	Freely soluble in methanol, chloroform, DMSO, and DMF; poorly soluble in water.
Purity Testing Method	HPLC
Structural Identification Method	NMR/MS
Storage Conditions	−20 °C, keep in dark place.

Other Properties

DESCRIPTION

Cyanine7 NHS Ester is a reactive near-infrared dye (ex/em 750/773 nm) for covalent amine conjugation. This non-sulfonated reagent forms stable amide bonds with primary amines (pH 7.5-9.0), enabling efficient labeling of proteins, peptides, and amine-functionalized surfaces. Exhibits excellent solubility in anhydrous DMSO/DMF (>10 mM) and optimal fluorescence for deep-tissue imaging.
For aqueous applications, use sulfo-Cyanine7 NHS Ester. Store desiccated at -20°C under inert atmosphere.

SAFETY INFORMATION

Symbol GHS
Hazard Code
Risk Statements
Safety Statements
RIDADR
WGK Germany
RTECS
F
Hazard Class
Packing Group
HS Code
Toxicity
Autoignition Temperature

1. Saxena, T.; Karumbaiah, L.; Gaupp, E.A.; Patkar, R.; Patil, K.; Betancur, M.; Stanley, G.B.; Bellamkonda, R.V. The impact of chronic blood-brain barrier breach on intracortical electrode function. Biomaterials, 2013, 34(20), 4703-4713. doi: 10.1016/j.biomaterials.2013.03.007

2. Gluz, E.; Mizrahi, D.M.; Margel, S. Synthesis and characterization of new poly(ethylene glycol)bisphosphonate vinylic monomer and non-fluorescent and NIR-fluorescent bisphosphonate micrometer-sized particles. Polymer, 2013, 54(2), 565-571. doi: 10.1016/j.polymer.2012.11.071

3. Gluz, E.; Grinberg, I.; Corem-Salkmon, E.; Mizrahi, D.; Margel, S. Engineering of new crosslinked near-infrared fluorescent polyethylene glycol bisphosphonate nanoparticles for bone targeting. Journal of Polymer Science, Part A: Polymer Chemistry, 2013, 51(20), 4282-4291. doi: 10.1002/pola.26858

4. Skaat, H.; Corem-Salkmon, E.; Grinberg, I.; Last, D.; Goez, D.; Mardor, Y.; Margel, S. Antibody-conjugated, dual-modal, near-infrared fluorescent iron oxide nanoparticles for antiamyloidgenic activity and specific detection of amyloid-β fibrils. International Journal of Nanomedicine, 2013, 8, 4063–4076. doi: 10.2147/ijn.s52833

5. Zhao, Y.; Meek, G.A.; Levine, B.G.; Lunt, R.R. Near-Infrared Harvesting Transparent Luminescent Solar Concentrators. Advanced Optical Materials, 2014, 2(7), 606-611. doi: 10.1002/adom.201400103

6. Novo, L.; Rizzo, L.Y.; Golombek, S.K.; Dakwar, G.R.; Lou, B.; Remaut, K.; Mastrobattista, E.; van Nostrum, C.F.; Jahnen-Dechent, W.; Kiessling, F. et al. Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy. Journal of Controlled Release, 2014, 195, 162-175. doi: 10.1016/j.jconrel.2014.08.028

7. Lin, X.; Zhu, H.; Luo, Z.; Hong, Y.; Zhang, H.; Liu, X.; Ding, H.; Tian, H.; Yang, Z. Near-Infrared Fluorescence Imaging of Non-Hodgkin's Lymphoma CD20 Expression Using Cy7-Conjugated Obinutuzumab. Molecular Imaging and Biology, 2014. doi: 10.1007/s11307-014-0742-3

8. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p

9. Brady, M.L.; Raghavan, R.; Singh, D.; Anand, P.; Fleisher, A.S.; Mata, J.; Broaddus, W.C.; Olbricht, W.L. In vivo performance of a microfabricated catheter for intraparenchymal delivery. Journal of Neuroscience Methods, 2014, 229, 76-83. doi: 10.1016/j.jneumeth.2014.03.016

10. Choi, E.B.; Choi, J.; Bae, S.R.; Kim, H.-O.; Jang, E.; Kang, B.; Kim, M.-H.; Kim, B.; Suh, J.-S.; Lee, K. et al. Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport. Nano Research, 2015, 8(4), 1169–1179. doi: 10.1007/s12274-014-0597-6

Key Documents

OCY702

Symbol GHS

Hazard Code

Risk Statements

Safety Statements

RIDADR

WGK Germany

RTECS

F

Hazard Class

Packing Group

HS Code

Toxicity

Autoignition Temperature

1. Saxena, T.; Karumbaiah, L.; Gaupp, E.A.; Patkar, R.; Patil, K.; Betancur, M.; Stanley, G.B.; Bellamkonda, R.V. The impact of chronic blood-brain barrier breach on intracortical electrode function. Biomaterials, 2013, 34(20), 4703-4713. doi: 10.1016/j.biomaterials.2013.03.007

2. Gluz, E.; Mizrahi, D.M.; Margel, S. Synthesis and characterization of new poly(ethylene glycol)bisphosphonate vinylic monomer and non-fluorescent and NIR-fluorescent bisphosphonate micrometer-sized particles. Polymer, 2013, 54(2), 565-571. doi: 10.1016/j.polymer.2012.11.071

3. Gluz, E.; Grinberg, I.; Corem-Salkmon, E.; Mizrahi, D.; Margel, S. Engineering of new crosslinked near-infrared fluorescent polyethylene glycol bisphosphonate nanoparticles for bone targeting. Journal of Polymer Science, Part A: Polymer Chemistry, 2013, 51(20), 4282-4291. doi: 10.1002/pola.26858

5. Zhao, Y.; Meek, G.A.; Levine, B.G.; Lunt, R.R. Near-Infrared Harvesting Transparent Luminescent Solar Concentrators. Advanced Optical Materials, 2014, 2(7), 606-611. doi: 10.1002/adom.201400103

7. Lin, X.; Zhu, H.; Luo, Z.; Hong, Y.; Zhang, H.; Liu, X.; Ding, H.; Tian, H.; Yang, Z. Near-Infrared Fluorescence Imaging of Non-Hodgkin's Lymphoma CD20 Expression Using Cy7-Conjugated Obinutuzumab. Molecular Imaging and Biology, 2014. doi: 10.1007/s11307-014-0742-3

8. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p

9. Brady, M.L.; Raghavan, R.; Singh, D.; Anand, P.; Fleisher, A.S.; Mata, J.; Broaddus, W.C.; Olbricht, W.L. In vivo performance of a microfabricated catheter for intraparenchymal delivery. Journal of Neuroscience Methods, 2014, 229, 76-83. doi: 10.1016/j.jneumeth.2014.03.016

10. Choi, E.B.; Choi, J.; Bae, S.R.; Kim, H.-O.; Jang, E.; Kang, B.; Kim, M.-H.; Kim, B.; Suh, J.-S.; Lee, K. et al. Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport. Nano Research, 2015, 8(4), 1169–1179. doi: 10.1007/s12274-014-0597-6

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Key Documents

OCY702

Symbol GHS

Hazard Code

Risk Statements

Safety Statements

RIDADR

WGK Germany

RTECS

F

Hazard Class

Packing Group

HS Code

Toxicity

Autoignition Temperature

OCY713

Water-soluble Cyanine7 maleimide

OCY712

Cyanine7 hydrazide

OCY711

Cyanine7 Trans-Cyclooctene

OCY710

Cyanine7 SH

OCY709

Cyanine7 amine

OCY708

Cyanine7 Biotin

OCY707

Cyanine7 DBCO

OCY706

Cyanine7 alkyne

OCY705

Cyanine7 azide

OCY704

Cyanine7 tetrazine

OCY703

Cyanine7 maleimide

OCY701

Cyanine7 carboxylic acid

1. Saxena, T.; Karumbaiah, L.; Gaupp, E.A.; Patkar, R.; Patil, K.; Betancur, M.; Stanley, G.B.; Bellamkonda, R.V. The impact of chronic blood-brain barrier breach on intracortical electrode function. Biomaterials, 2013, 34(20), 4703-4713. doi: 10.1016/j.biomaterials.2013.03.007

2. Gluz, E.; Mizrahi, D.M.; Margel, S. Synthesis and characterization of new poly(ethylene glycol)bisphosphonate vinylic monomer and non-fluorescent and NIR-fluorescent bisphosphonate micrometer-sized particles. Polymer, 2013, 54(2), 565-571. doi: 10.1016/j.polymer.2012.11.071

3. Gluz, E.; Grinberg, I.; Corem-Salkmon, E.; Mizrahi, D.; Margel, S. Engineering of new crosslinked near-infrared fluorescent polyethylene glycol bisphosphonate nanoparticles for bone targeting. Journal of Polymer Science, Part A: Polymer Chemistry, 2013, 51(20), 4282-4291. doi: 10.1002/pola.26858

5. Zhao, Y.; Meek, G.A.; Levine, B.G.; Lunt, R.R. Near-Infrared Harvesting Transparent Luminescent Solar Concentrators. Advanced Optical Materials, 2014, 2(7), 606-611. doi: 10.1002/adom.201400103

7. Lin, X.; Zhu, H.; Luo, Z.; Hong, Y.; Zhang, H.; Liu, X.; Ding, H.; Tian, H.; Yang, Z. Near-Infrared Fluorescence Imaging of Non-Hodgkin's Lymphoma CD20 Expression Using Cy7-Conjugated Obinutuzumab. Molecular Imaging and Biology, 2014. doi: 10.1007/s11307-014-0742-3

8. Graen, T.M.D.; Hoefling, M.; Grubmüller, H. AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, 2014, 10(12), 5505-5512. doi: 10.1021/ct500869p

9. Brady, M.L.; Raghavan, R.; Singh, D.; Anand, P.; Fleisher, A.S.; Mata, J.; Broaddus, W.C.; Olbricht, W.L. In vivo performance of a microfabricated catheter for intraparenchymal delivery. Journal of Neuroscience Methods, 2014, 229, 76-83. doi: 10.1016/j.jneumeth.2014.03.016

10. Choi, E.B.; Choi, J.; Bae, S.R.; Kim, H.-O.; Jang, E.; Kang, B.; Kim, M.-H.; Kim, B.; Suh, J.-S.; Lee, K. et al. Colourimetric redox-polyaniline nanoindicator for in situ vesicular trafficking of intracellular transport. Nano Research, 2015, 8(4), 1169–1179. doi: 10.1007/s12274-014-0597-6

omichem

SIGN UP & SAVE 10%

Applies to full-price items only. Online exclusive.

By submitting your email, you agree to:

Receive promotional emails from OMICHEM (unsubscribe anytime)

Our Terms of Use (including arbitration clause)

Data sharing with service providers as per our Privacy Policy